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Clinically relevant contraindications to GLP 1 receptor agonists (semaglutide, liraglutide, dulaglutide, tirzepatide behaves similarly for most). Absolute contraindications 1. Personal or family history of Medullary Thyroid Carcinoma (MTC) 2. Patients How Would Authorizing Medicare to Cover Anti Obesity Medications Affect the Federal Budget? Congressional Budget Office GLP 1 drugs: Illuminating their full side effect profile Drug Discovery News Struggling with GLP 1 therapy side effects? You're not alone. This Clinician Guide: Managing Common GLP 1 Receptor Agonist Side Effects provides practical tips on recognizing, preventing and managing gastrointestinal and nutritional side effects. Full article: GLP 1 receptor agonists: new kids in the block of renoprotection for people with type 2 diabetes and chronic kidney disease Glucagon like peptide 1 receptor agonists in diabetic kidney disease: A review of their kidney and heart protection ScienceDirect
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Best in 7 days
Best in 7 days
Best in 7 days
Best in 7 days
4.9 ★★★★★
Based on 791 reviews
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Product Reviews
★★★★★ 5
Durable
Color: S6-muti-color
The balls are great for chewers. The squeaky didn’t last long but they are perfect for the ball launcher.
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Reviewed in the United States on May 18, 2026
★★★★★ 4
The squeeker isn't durable, but the balls themselves are.
Color: S6-muti-color, Color: S6-muti-color
I have two 70+lb, ball obsessed dogs (a field bred Golden Retriever, and an Old Time Scotch Collie), and these balls are living up to the abuse they're receiving.
In the fall we always lose a ball or two in the yard due to getting lost in leaves or longer grass, so I always try and buy a multi pack at the start of the season, so went with these this year. I'm glad I did. Great price for a 6 pack, they fit the medium Chuck-It launcher (a little loosely, but they throw just fine), have great bounce, they FLOAT (which means I didn't lose any at the beach), and they're super durable to the dreaded "mouth squish." The squeaker dies pretty quick, like, within a day, but it isn't the kind that can fall out or choke your dog, so no worries there.
The boys are happy, I'm happy, my wallet is happy - I've already ordered another pack.
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Reviewed in the United States on November 2, 2024
★★★★★ 5
Good balls
Color: S6-glow
My dog is a chewer, and these have held up for close to a year actually a pretty good product
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Reviewed in the United States on May 27, 2026
★★★★★ 3
Disappointed
Color: S6-muti-color
These were great for about 20 minutes then they stopped squeaking...we have 2 left that I have saved but the other 4 do not squeak anymore...disappointed as my dog loves to squeak things...would not buy these again...My dog is only an 8lb dog too...but he can still play with the balls without the squeak...
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Reviewed in the United States on April 26, 2026
★★★★★ 5
Great Value for a ball my dog loves!
Color: S6-muti-color
I wish these ball were in the subscription program! My dog gets sooo excited by the new ball, but her interest in things lasts for a few days. She kills the squeak within 11minutes, but the squeaker stays in place rather than becoming a chocking or swallow hazard, and she still loves to chew it. Next, we must throw the ball approximately 723 times the first day, possibly 496 times on day 2, and just 3- 4 on day 3, at which point she will chase the ball before hollering "it's over here if you need it," while she checks on the chipmunk den. We currently have 17 of these balls in our yard (because we have given several leftovers to a less discriminating doodle next door). These balls hold up really well, get her extremely active for the first couple of days, and are a much cheaper than doggie daycare (after an active morning with a new ball, she is happy to chew on it and sleep much of the day). I always have these on hand!
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Reviewed in the United States on November 22, 2025
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